Ying-Yong Zhao Selected Research

poricoic acid A

7/2020	Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
1/2020	Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
12/2019	Microbiome-metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease.
1/2019	Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.
1/2019	Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.

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Ying-Yong Zhao Research Topics

Disease

44	Fibrosis (Cirrhosis) 10/2023 - 12/2011
23	Chronic Renal Insufficiency 10/2023 - 10/2012
18	Inflammation (Inflammations) 10/2023 - 12/2014
17	Neoplasms (Cancer) 02/2021 - 07/2010
16	Chronic Kidney Failure (Chronic Renal Failure) 12/2024 - 12/2011
13	Kidney Diseases (Kidney Disease) 01/2024 - 08/2013
7	Diabetic Nephropathies (Diabetic Nephropathy) 12/2024 - 06/2013
6	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2024 - 01/2022
6	Proteinuria 09/2023 - 12/2011
5	Ureteral Obstruction 12/2020 - 01/2018
5	Hyperlipidemias (Hyperlipidemia) 04/2017 - 01/2014
4	Hypertension (High Blood Pressure) 03/2022 - 01/2019
3	IGA Glomerulonephritis (IGA Nephropathy) 01/2023 - 06/2013
3	Dyslipidemias (Dyslipidemia) 02/2021 - 01/2014
3	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 01/2014
3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2014
3	Anemia 01/2017 - 12/2011
3	Edema (Dropsy) 12/2014 - 04/2013
2	Atherosclerosis 10/2023 - 01/2014
2	Acute Kidney Injury (Acute Renal Failure) 03/2021 - 01/2019
2	Disease Progression 02/2021 - 01/2019
2	Renal Cell Carcinoma (Grawitz Tumor) 11/2020 - 01/2019
2	Hepatocellular Carcinoma (Hepatoma) 11/2020 - 04/2011
2	Dysbiosis 01/2020 - 12/2019
2	Hypoxia (Hypoxemia) 01/2019 - 01/2019
2	Chronic Tubulointerstitial Nephropathy 01/2018 - 02/2016
2	Uremia 12/2017 - 01/2016
2	Breast Neoplasms (Breast Cancer) 10/2017 - 09/2017
2	Body Weight (Weight, Body) 07/2017 - 12/2011
2	Obesity 09/2016 - 01/2014
2	Metabolic Diseases (Metabolic Disease) 10/2015 - 10/2014
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2023
1	Renal Insufficiency (Renal Failure) 10/2023
1	Pathologic Processes 10/2023

Drug/Important Bio-Agent (IBA)

16	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2014
15	Adenine FDA LinkGeneric 02/2021 - 02/2012
13	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2024 - 01/2019
12	CateninsIBA 06/2023 - 01/2017
9	LipidsIBA 01/2023 - 01/2014
8	Proteins (Proteins, Gene)FDA Link 06/2023 - 05/2014
8	ergosta-4,6,8(14),22-tetraen-3-oneIBA 01/2021 - 10/2010
7	CreatinineIBA 03/2021 - 12/2011
7	Therapeutic UsesIBA 01/2021 - 10/2012
6	LigandsIBA 01/2022 - 01/2019
5	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023 - 01/2018
5	NF-kappa B (NF-kB)IBA 01/2023 - 12/2016
5	Urea (Carbamide)FDA LinkGeneric 03/2021 - 12/2011
5	AcidsIBA 12/2020 - 12/2017
5	TriterpenesIBA 12/2020 - 04/2013
5	poricoic acid AIBA 07/2020 - 01/2019
4	Tryptophan (L-Tryptophan)FDA Link 01/2024 - 01/2019
4	RNA (Ribonucleic Acid)IBA 01/2020 - 09/2017
4	Fatty Acids (Saturated Fatty Acids)IBA 07/2017 - 02/2013
4	DiureticsIBA 12/2014 - 04/2013
3	EicosanoidsIBA 01/2024 - 02/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 12/2016
3	Lipoproteins (Lipoprotein)IBA 01/2023 - 01/2017
3	Uremic ToxinsIBA 02/2021 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 09/2017
3	Complex MixturesIBA 11/2018 - 08/2013
3	aristolochic acid I (aristolochic acid)IBA 12/2016 - 12/2011
2	Sodium Glutamate (Accent)IBA 09/2023 - 06/2023
2	EnzymesIBA 01/2023 - 01/2019
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2019
2	NitrogenIBA 01/2023 - 12/2011
2	ReninIBA 01/2022 - 01/2018
2	shenkangIBA 01/2022 - 01/2021
2	Long Noncoding RNAIBA 03/2021 - 01/2019
2	Bile Acids and Salts (Bile Acids)IBA 02/2021 - 02/2016
2	ElectrolytesIBA 02/2021 - 12/2017
2	Advanced Glycation End ProductsIBA 01/2021 - 01/2019
2	FlavonoidsIBA 01/2020 - 01/2019
2	MelatoninIBA 01/2019 - 01/2019
2	MicroRNAs (MicroRNA)IBA 01/2019 - 01/2018
2	trimethyloxamine (trimethylamine N-oxide)IBA 01/2019 - 01/2016
2	ethyl acetateIBA 02/2018 - 02/2016
2	Polysaccharides (Glycans)IBA 01/2017 - 04/2013
2	Glycerophospholipids (Phosphoglycerides)IBA 02/2016 - 02/2015
2	IndicanIBA 01/2016 - 02/2013
2	AntioxidantsIBA 09/2015 - 04/2013
2	PhytochemicalsIBA 09/2015 - 08/2013
2	Triglycerides (Triacylglycerol)IBA 08/2015 - 01/2014
1	indoleIBA 01/2024
1	CollagenIBA 10/2023
1	Extracellular Matrix ProteinsIBA 10/2023
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2023
1	Indicators and Reagents (Reagents)IBA 10/2023
1	Fibronectins (Fibronectin)IBA 10/2023
1	Mitochondrial DNA (mtDNA)IBA 10/2023
1	Phospholipase A2 ReceptorsIBA 10/2023
1	SirtuinsIBA 08/2023
1	podocalyxinIBA 06/2023

Therapy/Procedure

17	Therapeutics 09/2023 - 06/2013
3	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2024 - 04/2013
3	Transplantation 12/2024 - 01/2018
3	Kidney Transplantation 01/2023 - 03/2021
3	Renal Dialysis (Hemodialysis) 01/2022 - 12/2017
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2021
2	Nephrectomy 07/2020 - 01/2018
1	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2024